My opinion on every single organelle in the game.
Before I begin, I feel like this version is about producing enough ATP. Everything else kind of doesn’t matter now.
Also, as it was mentioned somewhere, the game behaves wonky when you grow. It seems like your atp production doesnt grow.
What that means - right now you need to produce a lot of atp.
S Tier - always use
Mitochondria - 45 mp, converts 1 oxy+0.2 glucose -> 45 ATP, gives 2 storage space, takes 2 hexes.
Mitochondria is the go-to way to increase your atp production, combo: 5 mitochondria + 1 chloroplast could be build for three evolutions and gives you 34 free atp/second(47 - 5*2-3). Plus, it has a 22.5 cost-per hex ratio, which is really good.
In the current circumstances it is not 34, but 34 - 5*2 - 3 = 21, because ATP production does not grow when cell grows. And you have to maintain the nucleus, which also doubles. That means, that you kind of have to go for this combo.
Chloroplast - 55 mp, converts 0.09 co2 -> 1 glucose, gives 2 storage space, takes three hexes.
Ok, first of all, the mitochondria+chloroplast combo, second - it is the best glucose producer, third - even without that it has the best cost-per-hex ratio aside of nucleus, so I would sometimes use it for making it easier to engulf others.
A Tier - almost always use
Metabolosome - 45 mp, converts 1 oxy+1 glu -> 38 ATP, gives 1 storage space, takes one hex.
It is basically a mitochondria, but it consumes more glucose. It is really not a problem, since everything produces glucose. So, the main difference is that mytochondria gives you one more hex for the same price, which is good for engulfing stuff. And it is also the best option if you want to go for a quick nucleus.
Nucleus - 100 mp, gives you access to eukaryotic organelles, gives 15 storage space, takes 10 hex. Can only be placed once.
Well, I would like to talk about nucleus in a separate post. Right now I only want to tell that it is the best cost-per-hex organelle, and it has a better cost-per-storage ratio than a cytoplasm. So, if you could place more than one, I would go for it.
B Tier - just a good organelle
Vacuole - 50 mp, gives 15 storage space, takes one hex
Vacuole is finally relevant. It is a good choise, if you have to stop every three seconds to recharge your atp. Sad thing is that vacuole will probably be not relevant after the bug fix
Cytoplasm - 30 mp cost, performs glycolysis, gives 4 storage space, takes one hex.
This organelle is cery weird. It cost-per-hex is 30, which is one of the worst in the game, so it can’t be used for making yourself bigger, it performs glycolysis, but in that category it gets outclassed by literally anything, it gives storage space, but vacuole does it better.
The worst thing is the price. While most organelles cost 45 or 55, which makes for nice 45+55 combo, cytoplasm costs 30, so, if you put it in combination with something, you are just wasting at least 15 mp, which just feels bad.
But here is the thing. While cytoplasm is really bad in combination with other organelles, it suddenly becomes good when used in combination with itself. For 90 mp you can have 12 ATP and 12 storage space, which is almost as much as having two metabolosomes and a vacuole(13 atp and 15 storage space for 140 mp). That combo makes cytoplasm the best choise in oxygen-free environments. It is not top tier, because 12 apt is not enough for gan3 nucleus.
Toxin vacuole - 70 mp, converts 1 oxy + 5 ATP -> 5 oxytoxy, gives 5 storage space, takes one hex.
Well, I have mixed feelings about this organelle. On the one hand, it is the only way of ranged combat and the only way to kill enemies which are bigger than you, but on the other hand there are a lot of prokaryotes swimming around for you to eat. It could be good in some cases, and it is fun to use. The biggest downside is that you have to add another mitochondria to be able to keep up with the atp costs.
Edit: well, apparently it is the best late-game choise, because by gen10 everything is big and you get really much from one kill. Also, by that time ATP becomes less of a problem.
C Tier - situational use
Chemoplast - 45 mp, performs glycolysis, converts 0.09 co2+1 sulf -> 2 glu, gives 2 storage space, takes tow hexes.
This organelle is actually the fastest glucose producer, so you can totally go for it. The only problem is that you dont really need much glucose to produce a lot of atp. Otherwise this organelle would be in B tier.
Flagellum - 55 mp, gives speed, gives one storage space, takes one hex.
Edit: the movement speed increase shown in the editor must be bugged because two flagella could drastically increase your speed. ATP cost is really high for them though and you probably dont want to go for them until the late game.
Why only C-Tier for the only organelle that gives you a speed advantage? Because you dont need speed to shoot big cells in the late game and because AI cells cant use flagellas properly, so your basic movement speed should be enough to escape opponents that should be much faster than you.
D Tier - almost never use
Chromatophore - 55 mp, performs glycolysis, converts 0.09 co2->0.015 glu, gives one storage space, takes one hex.
This organelle gives you 4 ATP/sec for free. Plus a bonus of 1 glucose every 40 seconds. While this is good, 4 ATP is much less than what mitochondria and metabolosome could give you. I can see this work in environments with no oxygen and co2 whatsoever. Otherwise mitochondria+chloroplast is a much better alternative.
Rusticyanin - 45 mp, turns 0.021oxy+0.09co2+0.175iron -> 10 ATP, gives 1 storage space, takes one hex.
This organelle turns iron straight into ATP. It is so low in the list because you need to have both oxygen and co2 to make this work, and you need to find chunks of iron. The only benefit of this organelle - it does not require glucose, but it is too easy to find glucose in the current meta.
And, if you have oxygen and co2, you can just use mitochondrion+chloroplast combo.
NFP - 50 mp, converts 1 oxy + 5 atp -> 0.5 ammonia, gives 2 storage space, takes two hexes.
This organelle has good stats now, yay. You can put two of them per evolution, which would drain 10 atp/sec, but give you 60 ammonia after only a minute. The only problem is that you need phosphates more often than ammonia, and the meta is too fast-paced for this organelle to really shine.
F Tier - never use
Chemosynthisizing Proteins - 45 mp, performs glycolysis, converts 1 co2+1 sulf -> 1 glu, gives 1 storage space, takes one hex.
The biggest problem with this organelle is works 11 times slower than the chemoplast and it provides only 0.09 glucose per second. That is just ridiculous.
Nitrogenase - 55 mp, converts 2 N + 10 ATP -> 0.02 ammonia, gives 2 storage, takes one hex
This new thing… First of all, it drains 3 ATP per second. Second - it takes 10 ATP to produce 0.02 ammonia. That is 500 ATP per 1 ammonia. Just never use that.
Right now the game is balanced around atp production and there will be some clear winners and losers in that category, no matter how much rebalancing will be going on. All of the D-tier organelles are so low because they require ATP(which is the limiting factor now) or they shine when there is not a lot of glucose.